Bridging the literature gap: Intravenous propofol for non-operating room anaesthesia in paediatric Wilson’s disease with autism spectrum disorder
Deep Sengupta · 2026
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Description
Deep Sengupta writes a 2026 letter on anaesthesia outside the operating room for a child with Wilson's disease and autism. The case involved an 11-year-old boy weighing 32 kilograms who needed an MRI scan. Wilson's disease impairs the liver and copper handling, while autism with profound hyperactivity makes lying still for scanning impossible without deep sedation.
Published guidance, Sengupta notes, covers major surgery in Wilson's disease almost exclusively, stressing liver harm, kidney risk from copper, and odd responses to muscle relaxants. Guidance for sedation in an isolated MRI suite, above all with severe behaviour conditions added, is nearly absent. The letter presents intravenous propofol use in that gap and reviews the child's ongoing medicines.
Catalog record
| CREATOR | Deep Sengupta |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 6041 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |