Epigenetic and microRNA-mediated regulation of pulmonary fibrosis and immune dysregulation in fatal COVID-19
Gabriela Casani Cardoso, Regiane Stafim da Cunha, Guilherme Miniskiskosky, Cleber Machado-Souza, Lucia de Noronha, Caroline Busatta Vaz de Paula, Felipe Francisco Tuon, Edneia Amancio de Souza Ramos Cavalieri · 2026
Read Epigenetic and microRNA-mediated regulation of pulmonary fibrosis and immune dysregulation in fatal COVID-19 by Gabriela Casani Cardoso, Regiane Stafim da Cunha, Guilherme Miniskiskosky, Cleber Machado-Souza, Lucia de Noronha, Caroline Busatta Vaz de Paula, Felipe Francisco Tuon, Edneia Amancio de Souza Ramos Cavalieri (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13321725.txt.
Description
Gabriela Casani Cardoso and co-authors studied lung tissue from fatal COVID-19 cases in this 2026 paper. Severe disease can scar the lungs and disturb immune control. The team asked how chemical marks on DNA and small regulatory RNAs shape that damage.
They measured gene and protein levels, DNA marks, and small RNA profiles in the tissue. Several genes tied to tissue buildup and to viral entry had changed levels, and some showed mark-based control. Two small RNAs fell, while others rose. Pathways for cell death and growth signals were active, while vessel and immune pathways were muted. The authors read the pattern as scarring plus immune drift in severe cases.
Catalog record
| CREATOR | Gabriela Casani Cardoso, Regiane Stafim da Cunha, Guilherme Miniskiskosky, Cleber Machado-Souza, Lucia de Noronha, Caroline Busatta Vaz de Paula, Felipe Francisco Tuon, Edneia Amancio de Souza Ramos Cavalieri |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |