Metabolism, autophagy, and cell death: The triangular axis in tumor survival and therapeutic resistance
Wen-Dong Wan, Muhammad Tufail, Can-Hua Jiang, Ning Li · 2026
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Description
Wen-Dong Wan and co-authors review a three way survival web in tumors in a 2026 article on metabolism, self eating, and cell death. Tumor cells live under steady stress from low food, low oxygen, and drug attack, and they lean on linked tricks to hold on. Cells rewire food burning for growth, eat their own parts to tide over lean spells, and dodge death signals that should kill them.
Each leg of the triangle feeds the others, and their joint play shapes how tumors grow and shrug off care. Key paths that run the web are mapped, along with death styles that care may still force. Turning the map into drugs will need sharp markers and drug pairs that cut more than one leg at once, the review argues.
Catalog record
| CREATOR | Wen-Dong Wan, Muhammad Tufail, Can-Hua Jiang, Ning Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 129306 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |