Multi-targeted biomimetic CeO₂-based nanoplatform for sepsis therapy via mitochondrial homeostasis
Xiaolin Tan, Zaili Zhang, Mingzhe Wu, Yuan Tan, Xue Zhang, Chang Li, Zhifeng Wen, Yanxia Lin, Jun Chen, Yao Li · 2026
Read Multi-targeted biomimetic CeO₂-based nanoplatform for sepsis therapy via mitochondrial homeostasis by Xiaolin Tan, Zaili Zhang, Mingzhe Wu, Yuan Tan, Xue Zhang, Chang Li, Zhifeng Wen, Yanxia Lin, Jun Chen, Yao Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13320434.txt.
Description
Xiaolin Tan and co-authors build a cloaked mineral particle for sepsis care in a 2026 mouse study. Sepsis is a body wide overreaction to infection that floods tissues with harmful oxygen forms, skews immunity, and fails organs. Their particle uses a cerium mineral that soaks up those forms as a core, loads a broad germ killer inside, and wears immune cell skin as a coat.
The coat helps the particle dodge immune patrols, home to kin cells, and soak up bacterial toxin on contact. Dish tests showed strong germ kill, toxin capture, and swelling calm. In mice with gut puncture sepsis, the particle cut swelling signals in blood and organs, eased liver, kidney, and gut harm, and lifted survival while guarding cell power houses.
Catalog record
| CREATOR | Xiaolin Tan, Zaili Zhang, Mingzhe Wu, Yuan Tan, Xue Zhang, Chang Li, Zhifeng Wen, Yanxia Lin, Jun Chen, Yao Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56374 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |