Evaluation of the safety and potential genotoxicity of a high-purity mogroside ingredient containing siamenoside I produced from a modified strain of Yarrowia lipolytica
Amy L Mihalchik, Ashley Roberts, Jonathan LaCombe, Mel Lloyd, Candace Doepker, Alex Eapen · 2026
Read Evaluation of the safety and potential genotoxicity of a high-purity mogroside ingredient containing siamenoside I produced from a modified strain of Yarrowia lipolytica by Amy L Mihalchik, Ashley Roberts, Jonathan LaCombe, Mel Lloyd, Candace Doepker, Alex Eapen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13320431.txt.
Description
Amy L Mihalchik and co-authors run safety tests on a brew made sweetener from monk fruit compounds in a 2026 study. The mix, made by a tuned yeast, is rich in one sweet compound that is rare in plain fruit extracts sold to date. Since brew made forms had never had a full safety pass, gene harm tests and rat feeding trials were run to set safe intake.
No gene harm showed in bacterial or cell tests at the top doses used, run to trade lab standards. Rats fed the mix for twenty eight days and for ninety days showed no ill effects even at the top diet share tested, which sets the safe floor for intake math. With expected eat levels far below that floor, the mix reads as safe for food use.
Catalog record
| CREATOR | Amy L Mihalchik, Ashley Roberts, Jonathan LaCombe, Mel Lloyd, Candace Doepker, Alex Eapen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56720 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |