Effects of evolocumab on plasma coenzyme Q10 in patients with heterozygous familial hypercholesterolemia
Hayato Tada, Yasuaki Takeji, Masayuki Takamura · 2026
Read Effects of evolocumab on plasma coenzyme Q10 in patients with heterozygous familial hypercholesterolemia by Hayato Tada, Yasuaki Takeji, Masayuki Takamura (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13320416.txt.
Description
Hayato Tada and co-authors check whether a strong cholesterol drug drains a key cell fuel in a 2026 small study of inherited high cholesterol. Muscle aches on statin drugs have been blamed in part on low levels of that fuel, which statins can cut. A newer shot drug that blocks a cholesterol control protein is used when statins fail or hurt, yet its effect on the fuel was unknown.
Ten adults with one faulty gene copy, already on two oral drugs, added the shot and were rechecked at four weeks. Bad cholesterol fell by about half in the counts reported, and a second harmful fat fell too, while fuel levels held flat. Fuel shifts also showed no tie to fat drops. The shot may spare muscle prone patients that one risk.
Catalog record
| CREATOR | Hayato Tada, Yasuaki Takeji, Masayuki Takamura |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 13371 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |