Long-term evaluation of plasma electrolytic oxidation (PEO) surface-modified WE43MEO magnesium alloy screws and plates reveals safe and controlled degradation in a 18-month minipig model

Alexander Kopp, Alina Schmitz, Henri Kreiker, Heilwig Fischer, Ana Prates Soares, Katharina Schmidt-Bleek, Georg Duda, Henning Hanken, Nadja Kröger, Max Heiland, Ralf Smeets, Carsten Rendenbach · 2026

Read Long-term evaluation of plasma electrolytic oxidation (PEO) surface-modified WE43MEO magnesium alloy screws and plates reveals safe and controlled degradation in a 18-month minipig model by Alexander Kopp, Alina Schmitz, Henri Kreiker, Heilwig Fischer, Ana Prates Soares, Katharina Schmidt-Bleek, Georg Duda, Henning Hanken, Nadja Kröger, Max Heiland, Ralf Smeets, Carsten Rendenbach (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13320413.txt.

Description

Alexander Kopp and co-authors follow dissolving magnesium bone screws in mini pigs for eighteen months in a 2026 study. Magnesium gear can hold bone while it heals and then melt away, which spares a second surgery, but fast melt can break hold and puff gas pockets. A plasma coat meant to slow the melt was tested against bare gear of the same alloy in leg and arm bones.

Coated and bare screws and plates sat in non broken bones and were checked by fine scans and tissue cuts after removal. Bare gear had melted away in full, while coated gear kept part of its frame, which shows the coat worked. Coated gear also sat in richer mature bone and caused no late harm. The coat may suit load bearing fixings.

Catalog record

CREATORAlexander Kopp, Alina Schmitz, Henri Kreiker, Heilwig Fischer, Ana Prates Soares, Katharina Schmidt-Bleek, Georg Duda, Henning Hanken, Nadja Kröger, Max Heiland, Ralf Smeets, Carsten Rendenbach
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE56089
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13320413

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