MiR-139 modulates CD8+ T cells exhaustion by targeting CD28 in breast cancer
Jianrong Chen, Haiyong Zhang, Yanting Lv, Xiufang Li, Mengjun Hu · 2026
Read MiR-139 modulates CD8+ T cells exhaustion by targeting CD28 in breast cancer by Jianrong Chen, Haiyong Zhang, Yanting Lv, Xiufang Li, Mengjun Hu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13320287.txt.
Description
Jianrong Chen and co-authors study a tiny gene scrap that wears out killer immune cells in breast cancer in a 2026 article. The scrap is known to curb tumor cells themselves, yet its work inside the immune crowd around a tumor was unclear. Data bank checks first flagged it as unevenly voiced in breast tumors, then patient samples gave a closer look.
Samples from 32 patients showed higher scrap levels in killer cells inside tumors than in nearby healthy tissue. The scrap latches onto a co start switch those cells need and turns it down, while wear out marks on the cells rose. Tumors rich in the scrap also voiced more call signals that pull killer cells in. The scrap thus both recruits and blunts the same cells.
Catalog record
| CREATOR | Jianrong Chen, Haiyong Zhang, Yanting Lv, Xiufang Li, Mengjun Hu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 65438 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |