MicroFace maps microglial morphology remodeling, revealing spatial zones and bifurcated trajectories during brain microinjury recovery
Vatsal D. Jariwala, Shreya Ponnamma, Vidhya M. Ravi, Jürgen Beck, Ulrich G. Hofmann, Kevin Joseph · 2026
Read MicroFace maps microglial morphology remodeling, revealing spatial zones and bifurcated trajectories during brain microinjury recovery by Vatsal D. Jariwala, Shreya Ponnamma, Vidhya M. Ravi, Jürgen Beck, Ulrich G. Hofmann, Kevin Joseph (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13320269.txt.
Description
Vatsal D. Jariwala and co-authors present a software pipeline that maps shape change in brain guard cells after small injury in a 2026 study. Guard cells shift shape as they react to harm, from branchy at rest to round when alarmed, yet counting those shifts across huge image sets was slow by hand. Their tool rebuilds and measures each cell on its own from glow tagged photos.
The tool was run on 279510 guard cells from rodent brain after a probe prick injury. Shapes fell along a slope from branchy to round, sorted by span from the wound and by time since harm. Two paths split mid way, one toward short lived reactive forms and one toward rod like cells near the wound. Gene data hints the rod forms form a distinct immune tuning set.
Catalog record
| CREATOR | Vatsal D. Jariwala, Shreya Ponnamma, Vidhya M. Ravi, Jürgen Beck, Ulrich G. Hofmann, Kevin Joseph |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 88960 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |