Adversity as the key feature: neuroimaging profiles of subtypes from multiple depression risk factors

Jingying Zhou, Yaoyao Sun, Guorui Zhao, Junyuan Sun, Zhe Lu, Zhewei Kang, Yunqing Zhu, Rui Yuan, Jing Guo, Yuyanan Zhang, Wenjian Bi, Weihua Yue · 2026

Read Adversity as the key feature: neuroimaging profiles of subtypes from multiple depression risk factors by Jingying Zhou, Yaoyao Sun, Guorui Zhao, Junyuan Sun, Zhe Lu, Zhewei Kang, Yunqing Zhu, Rui Yuan, Jing Guo, Yuyanan Zhang, Wenjian Bi, Weihua Yue (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13319489.txt.

Description

Jingying Zhou and co-authors group life risk factors for low mood in a 2026 study of a large British health bank. Low mood grows from many strands of strain at once, yet how those strands cluster in one person was poorly known. Brain scans were also checked to see whether each cluster left a distinct mark.

Among 157317 adults who filled in a mental health survey, 24 strain and habit factors fell into three groups. Most people sat in a low risk group, while two smaller groups centered on harm in childhood or harm in adult life. Both strain groups faced far higher odds of low mood, each with its own main symptoms. Brain wiring also looked weaker in both groups.

Catalog record

CREATORJingying Zhou, Yaoyao Sun, Guorui Zhao, Junyuan Sun, Zhe Lu, Zhewei Kang, Yunqing Zhu, Rui Yuan, Jing Guo, Yuyanan Zhang, Wenjian Bi, Weihua Yue
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE54879
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13319489

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