Cervical strain elastography improves mid-trimester prediction of spontaneous preterm birth beyond cervical length: a single-center cohort study

Dongmei Zhang, Li Hou, Chunrong Li, Shiyue Peng, Liuying Zhou, Tongyong Luo · 2026

Read Cervical strain elastography improves mid-trimester prediction of spontaneous preterm birth beyond cervical length: a single-center cohort study by Dongmei Zhang, Li Hou, Chunrong Li, Shiyue Peng, Liuying Zhou, Tongyong Luo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13319053.txt.

Description

Dongmei Zhang and co-authors present a 2026 cohort study testing ultrasound elasticity of the cervix to predict early birth. Cervical length alone predicts poorly in women without symptoms. The study enrolled 275 singleton pregnancies at one centre. Scans ran between weeks 18 and 24 of pregnancy.

Early birth before 37 weeks occurred in 37 women, or 13.5 percent of the cohort. A stiffness measure at the inner opening predicted best alone, with an AUC of 0.797 in their analysis. Combining length with an inner-to-outer strain ratio lifted the AUC to 0.828 overall. That pairing beat either measure alone and gave better decision value. Sensitivity was 73 percent and specificity 82 percent at the chosen cut-off. Outside validation is still needed.

Catalog record

CREATORDongmei Zhang, Li Hou, Chunrong Li, Shiyue Peng, Liuying Zhou, Tongyong Luo
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE26111
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13319053

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