Quantitative traits of early-stage osteochondrosis lesions in porcine distal femurs are consistent with skeletal developmental age

Brittney P Kokinos, Pamela J Lang, Laura A Amundson, Matthew A Halanski, Thomas D Crenshaw · 2026

Read Quantitative traits of early-stage osteochondrosis lesions in porcine distal femurs are consistent with skeletal developmental age by Brittney P Kokinos, Pamela J Lang, Laura A Amundson, Matthew A Halanski, Thomas D Crenshaw (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13318846.txt.

Description

Brittney P Kokinos and co-authors examine, in 2026, early bone lesions in young pigs that model a joint disease of growing animals and children. Osteochondrosis begins as a focal failure of bone formation in growth regions. Early stages are rarely imaged before symptoms force treatment, so timing and location patterns are poorly known.

The team imaged thigh bones from pigs at several ages, using both computed tomography and magnetic resonance scans, with tissue checks in subsets. Abnormal growth plate widths appeared first, then defined growth plate lesions by twelve weeks. Lesions in the joint surface region appeared later and grew larger. A previously uncharacterised irregular lesion type was common at the oldest age. Both scan methods supported the same conclusions about developmental timing.

Catalog record

CREATORBrittney P Kokinos, Pamela J Lang, Laura A Amundson, Matthew A Halanski, Thomas D Crenshaw
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE66 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13318846

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