PD-1/TIGIT CD4⁺ T-Cell Signature for Risk Stratification of Post-Weaning Mortality in Venoarterial Extracorporeal Membrane Oxygenation Patients
Zengtao Wang, Xing Hao, Junyan Han, Chenglong Li, Liangshan Wang, Jing Chen, Jie Chen, Yu Cao, Yu Jiang, Haoyu Ji, Jiarui Li, Ju Zhang, Hong Wang, Mingxi Hua, Hui Zeng, Xiaotong Hou, Chen Chen · 2026
Read PD-1/TIGIT CD4⁺ T-Cell Signature for Risk Stratification of Post-Weaning Mortality in Venoarterial Extracorporeal Membrane Oxygenation Patients by Zengtao Wang, Xing Hao, Junyan Han, Chenglong Li, Liangshan Wang, Jing Chen, Jie Chen, Yu Cao, Yu Jiang, Haoyu Ji, Jiarui Li, Ju Zhang, Hong Wang, Mingxi Hua, Hui Zeng, Xiaotong Hou, Chen Chen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13317771.txt.
Description
Zengtao Wang and a large team hunt, in a 2026 study, for immune signs that predict death after patients successfully come off VA-ECMO, the heart-lung support machine. Many deaths happen after weaning, yet few markers sort who stays in danger.
Blood profiling covered 125 adults: 70 survivors, 33 who died on support, and 22 who died after weaning. Plain T cell counts did not separate the groups, but two CD4 subsets did: a PD-1 negative, TIGIT positive group ran high in those who later died, and its mirror ran low. Day-one readings sorted risk into bands where death rates ran from 10.53 to 70.59 percent across the scale. The signature could guide closer watching after weaning.
Catalog record
| CREATOR | Zengtao Wang, Xing Hao, Junyan Han, Chenglong Li, Liangshan Wang, Jing Chen, Jie Chen, Yu Cao, Yu Jiang, Haoyu Ji, Jiarui Li, Ju Zhang, Hong Wang, Mingxi Hua, Hui Zeng, Xiaotong Hou, Chen Chen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49377 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |