The integrated analysis of PRDX3 in lung cancer: biomarker potential and therapeutic target prospects
Qi Kong, Lei Zhang, Shuang Gong, Yue Wu, Jue Wang · 2026
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Description
Qi Kong and four co-authors mine public data for the role of one protein, PRDX3, in lung cancer. The protein ties to a rust-like cell death and had been flagged in tumor growth. Their 2026 study reads its levels across cancer types, lung subtypes, and patient groups.
Levels ran high in many tumors, lung ones among them, with little shift by sex, age, or stage. High levels tied to worse outlook in lung patients, most of all in one subtype. The protein's partners point to cell redox balance and the same rust-like death. Single-cell reads found it in both tumor and immune cells. The team names it a hopeful marker and drug target, with lab proof still to come.
Catalog record
| CREATOR | Qi Kong, Lei Zhang, Shuang Gong, Yue Wu, Jue Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |