Anthracaurisin ADiscovery of a Cytotoxic Nor-Sesquiterpene Dimer from Patagonian Anthracophyllum discolor
Bastien Petit, Ines Michrafy, Jordan Nafie, Grayce E. Dyer, Erin M. Marshall, Cristian Riquelme, Jaime R. Cabrera-Pardo, James A. Strother, Sandra Loesgen · 2026
Read Anthracaurisin ADiscovery of a Cytotoxic Nor-Sesquiterpene Dimer from Patagonian Anthracophyllum discolor by Bastien Petit, Ines Michrafy, Jordan Nafie, Grayce E. Dyer, Erin M. Marshall, Cristian Riquelme, Jaime R. Cabrera-Pardo, James A. Strother, Sandra Loesgen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13316986.txt.
Description
Bastien Petit and colleagues report a 2026 discovery from a Chilean fungus, Anthracophyllum discolor, a little-studied mushroom relative from Patagonia. Fungi hide vast chemical wealth, and this genus had never been mined, so the team grew it and screened its products.
They found anthracaurisin A, the first known fungal nor-sesquiterpene dimer, with strong cell-killing power in dishes and in living tests. Alongside it came one new and several known illudin compounds, whose exact 3D shapes the team pinned down. The work shows that even obscure mushroom genera can yield drug-like molecules, strengthening the case for wider fungal collecting and screening.
Catalog record
| CREATOR | Bastien Petit, Ines Michrafy, Jordan Nafie, Grayce E. Dyer, Erin M. Marshall, Cristian Riquelme, Jaime R. Cabrera-Pardo, James A. Strother, Sandra Loesgen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42327 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |