Redox Imbalance in ADHD: A Meta-Analysis of Oxidative Stress and Antioxidant Biomarkers (2010–2025)

Davoud Amiri, Lamberto Briziarelli, Swetang J Shah, Sara Amiri, Barry Karlsson, Amir Hossein Jalali Nadoushan · 2026

Read Redox Imbalance in ADHD: A Meta-Analysis of Oxidative Stress and Antioxidant Biomarkers (2010–2025) by Davoud Amiri, Lamberto Briziarelli, Swetang J Shah, Sara Amiri, Barry Karlsson, Amir Hossein Jalali Nadoushan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13316887.txt.

Description

Davoud Amiri and his team combine, in 2026, fifteen case-control studies on chemical oxidation balance in attention-deficit hyperactivity disorder. Oxidation damage and weak antioxidant defences have been put forward as part of the biology of this disorder, but single studies disagree. Their review covered work published from 2010 to 2025.

Damage markers were higher in ADHD, including malondialdehyde and a marker of DNA oxidation, and global oxidant measures also rose. Overall antioxidant levels and one key enzyme were lower, while two other enzymes showed no consistent difference. Variation between studies was low to moderate, and bias checks were clean. Effects were strongest in untreated children, weaker in adults or treated groups, which points to redox imbalance as a real but modest feature.

Catalog record

CREATORDavoud Amiri, Lamberto Briziarelli, Swetang J Shah, Sara Amiri, Barry Karlsson, Amir Hossein Jalali Nadoushan
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE23 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13316887

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