Mechanisms and therapeutic implications of galectins regulating Epstein–Barr virus infection
Jie-Yu Huang, Albright Dew Baua, Zih-Syuan Yang, Ching-I Tsui, Pin-Chen Chen, Wen-Hung Wang, Wanchai Assavalapsakul, Arunee Thitithanyanont, Yen-Hsu Chen, Sheng-Fan Wang · 2026
Read Mechanisms and therapeutic implications of galectins regulating Epstein–Barr virus infection by Jie-Yu Huang, Albright Dew Baua, Zih-Syuan Yang, Ching-I Tsui, Pin-Chen Chen, Wen-Hung Wang, Wanchai Assavalapsakul, Arunee Thitithanyanont, Yen-Hsu Chen, Sheng-Fan Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13316278.txt.
Description
Jie-Yu Huang and co-authors review in 2026 how galectins, sugar-binding proteins, shape Epstein-Barr virus infection and its linked diseases. The virus infects over 95 percent of adults worldwide and then hides for life in memory B cells. It is linked to cancers such as Hodgkin lymphoma and nasopharyngeal carcinoma, yet no licensed antiviral therapy exists.
Galectin-1, galectin-3, and galectin-9 stand out as major modulators, steering viral latency, immune escape, and tumor growth. Their dual roles in T-cell exhaustion and antiviral defense cut both ways. Targeting the galectin and glycan axis offers a possible treatment path.
Catalog record
| CREATOR | Jie-Yu Huang, Albright Dew Baua, Zih-Syuan Yang, Ching-I Tsui, Pin-Chen Chen, Wen-Hung Wang, Wanchai Assavalapsakul, Arunee Thitithanyanont, Yen-Hsu Chen, Sheng-Fan Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41545 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |