Metachronous Colorectal Carcinomas and Pancreatic Metastasis in Clinically Suspected Lynch Syndrome: An 18-Year Oncologic Course
Manana Jikurashvili, Giorgi Narimanishvili, Ilya Gotsadze, Armaz Mariamidze, David Chechelashvili, Mariam Gendzekhadze, Sopiko Matcharashvili, Giorgi Datunashvili, Salome Tchokhuri · 2026
Read Metachronous Colorectal Carcinomas and Pancreatic Metastasis in Clinically Suspected Lynch Syndrome: An 18-Year Oncologic Course by Manana Jikurashvili, Giorgi Narimanishvili, Ilya Gotsadze, Armaz Mariamidze, David Chechelashvili, Mariam Gendzekhadze, Sopiko Matcharashvili, Giorgi Datunashvili, Salome Tchokhuri (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13316268.txt.
Description
Manana Jikurashvili and co-authors describe, in 2026, a man whose bowel cancers returned repeatedly over eighteen years before cancer reached his pancreas. The patient had a strong family history of colorectal cancer and features pointing to Lynch syndrome, an inherited condition that raises cancer risk. Spread of bowel cancer to the pancreas is rare and hard to recognise.
Now aged 58, the man developed a mass in the body and tail of the pancreas during routine surveillance. Tissue examination showed a high-grade cancer with solid and nested growth and extensive dead tissue. Staining favoured a bowel origin and showed loss of two mismatch repair proteins. The authors stress careful clinic and pathology correlation and long-term team surveillance.
Catalog record
| CREATOR | Manana Jikurashvili, Giorgi Narimanishvili, Ilya Gotsadze, Armaz Mariamidze, David Chechelashvili, Mariam Gendzekhadze, Sopiko Matcharashvili, Giorgi Datunashvili, Salome Tchokhuri |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |