Expansion, functional diversification, and gene fusion events in the Ato protein family
Faezeh Ghasemi, Patrícia Ataíde, Cláudia Barata-Antunes, Yiannis Pyrris, João Alves, Vitor Fernandes, Rosana Alves, Alexandra Gomes-Gonçalves, Margarida Casal, Wouter Van Genechten, Jana Nysten, Alistair J.P. Brown, Patrick Van Dijck, Alexandros A. Pittis, George Diallinas, Isabel Soares-Silva, Sandra Paiva · 2026
Read Expansion, functional diversification, and gene fusion events in the Ato protein family by Faezeh Ghasemi, Patrícia Ataíde, Cláudia Barata-Antunes, Yiannis Pyrris, João Alves, Vitor Fernandes, Rosana Alves, Alexandra Gomes-Gonçalves, Margarida Casal, Wouter Van Genechten, Jana Nysten, Alistair J.P. Brown, Patrick Van Dijck, Alexandros A. Pittis, George Diallinas, Isabel Soares-Silva, Sandra Paiva (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13316224.txt.
Description
Faezeh Ghasemi and a very large team dissected in 2026 the expanded Ato transporter family in Candida albicans. That yeast lives in humans and must feed on alternative carbon when glucose runs low. Baker's yeast uses one Ato protein for acetate uptake, while Candida carries ten family members, most of unknown job.
Computer analysis of motifs, pore size, and binding sites suggested varied roles, and lab tests confirmed differing carboxylate transport. CaAto1 proved the main acetate carrier, driven by the proton gradient. Several members switched on with carboxylates and sat in the cell membrane, and gene fusion events shaped the family history.
Catalog record
| CREATOR | Faezeh Ghasemi, Patrícia Ataíde, Cláudia Barata-Antunes, Yiannis Pyrris, João Alves, Vitor Fernandes, Rosana Alves, Alexandra Gomes-Gonçalves, Margarida Casal, Wouter Van Genechten, Jana Nysten, Alistair J.P. Brown, Patrick Van Dijck, Alexandros A. Pittis, George Diallinas, Isabel Soares-Silva, Sandra Paiva |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 90543 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |