Sewage surveillance for assessing clinical antibiotic resistance prevalence: Combining metagenomic and phenotypic data
Carl-Fredrik Flach, Fanny Berglund, Gilbert Osena, Patricia MC Huijbers, DG Joakim Larsson · 2026
Read Sewage surveillance for assessing clinical antibiotic resistance prevalence: Combining metagenomic and phenotypic data by Carl-Fredrik Flach, Fanny Berglund, Gilbert Osena, Patricia MC Huijbers, DG Joakim Larsson (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13316215.txt.
Description
Carl-Fredrik Flach and colleagues compare in 2026 two ways to use sewage for tracking antibiotic resistance, against clinical rates. Lab testing of patients anchors resistance management but is missing in much of the world for lack of resources, and sewage checks could fill the gap cheaply.
Sewage from ten European countries was tested both by growing E. coli isolates for drug sensitivity and by metagenomic sequencing of resistance genes. Results were set against clinical resistance rates for four drug classes, including aminopenicillins and fluoroquinolones. Combining both sewage views may mirror clinic rates best.
Catalog record
| CREATOR | Carl-Fredrik Flach, Fanny Berglund, Gilbert Osena, Patricia MC Huijbers, DG Joakim Larsson |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37182 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |