Divergent early host transcriptional responses to H5N8 highly pathogenic avian influenza virus in chickens and ducks
Joanna Sajewicz-Krukowska, Katarzyna Domańska-Blicharz, Karolina Tarasiuk, Krzysztof Śmietanka, Barbara Marzec-Kotarska · 2026
Read Divergent early host transcriptional responses to H5N8 highly pathogenic avian influenza virus in chickens and ducks by Joanna Sajewicz-Krukowska, Katarzyna Domańska-Blicharz, Karolina Tarasiuk, Krzysztof Śmietanka, Barbara Marzec-Kotarska (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13315203.txt.
Description
Joanna Sajewicz-Krukowska and co-authors compared early lung gene activity in chickens and ducks infected with H5N8 bird flu in a 2026 study. Chickens often die quickly from this virus, while ducks tend to get milder or slower illness, and the reasons for that gap are still unclear.
RNA sequencing 24 hours after infection found a similar count of changed genes in both species, but the pattern differed. Chickens showed a focused response built around innate defense and swelling signals, including interferon and cytokine pathways. Ducks showed a wider, more even spread of changes across many functions. PCR checks confirmed selected genes.
Catalog record
| CREATOR | Joanna Sajewicz-Krukowska, Katarzyna Domańska-Blicharz, Karolina Tarasiuk, Krzysztof Śmietanka, Barbara Marzec-Kotarska |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39300 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |