Cardiac Biomarkers to Refine Pretest Probability for Coronary Obstruction and Predict Survival After Revascularization in Chronic Coronary Syndrome
Andrej Teren, Jeffrey Netto, Joachim Thiery, Holger Thiele, Christoph Stellbrink, Dennis Lawin, Thorsten Lawrenz, Anselm Artur Derda, Sylvia Henger, Holger Kirsten, Markus Scholz, Thorsten Kaiser · 2026
Read Cardiac Biomarkers to Refine Pretest Probability for Coronary Obstruction and Predict Survival After Revascularization in Chronic Coronary Syndrome by Andrej Teren, Jeffrey Netto, Joachim Thiery, Holger Thiele, Christoph Stellbrink, Dennis Lawin, Thorsten Lawrenz, Anselm Artur Derda, Sylvia Henger, Holger Kirsten, Markus Scholz, Thorsten Kaiser (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13315135.txt.
Description
Andrej Teren and colleagues test, in a 2026 study, whether blood biomarkers can sharpen two decisions in chronic coronary syndrome: who has obstructed arteries, and who gains from reopening them. The team enrolled 2,251 patients undergoing coronary angiography for disease and measured five biomarkers, then followed the cohort for a median of 12.6 years. Obstructive disease, at least half blockage of a major vessel, was present in 888 patients, or 39.4 percent of the group.
For diagnosis, only high-sensitivity troponin T added information, and its help grew as clinical likelihood shrank, boosting accuracy by 10.4 percent in the lowest-likelihood group. For prognosis, NT-proBNP dominated, predicting death across every treatment path. A threshold of 150 picograms per milliliter split the cohort sharply. Below it, survival was good with or without reopening. Above it, risk soared nearly sixfold yet revascularization cut mortality by about forty percent. The authors propose the pair as a triage duo.
Catalog record
| CREATOR | Andrej Teren, Jeffrey Netto, Joachim Thiery, Holger Thiele, Christoph Stellbrink, Dennis Lawin, Thorsten Lawrenz, Anselm Artur Derda, Sylvia Henger, Holger Kirsten, Markus Scholz, Thorsten Kaiser |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |