Autoimmune GFAP astrocytopathy with eosinophils on cerebrospinal fluid cytology and isolated spinal cord lesions on MRI: a case report
Dongdong Zhang, Yahan Song, Yongjie Bai, Junqiang Yan, Ruile Shen · 2026
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Description
Dongdong Zhang and co-workers report a 2026 case of an autoimmune brain and cord disorder with two rare twists. The disease, GFAP astrocytopathy, stems from antibodies against a cell protein and usually shows as brain and cord inflammation, often with clear brain scan changes.
Their patient was a 31-year-old woman with fever, headache, trouble passing urine, and signs of meningeal irritation. Her brain scan was clean, yet her spine scan showed patchy long lesions in the thoracic cord, standing alone. Spinal fluid held high pressure, extra cells, raised protein, and a share of 10 percent eosinophils on cell study, as stated in the report, a rare find in this disease. The case warns that a normal brain scan does not rule the disease out.
Catalog record
| CREATOR | Dongdong Zhang, Yahan Song, Yongjie Bai, Junqiang Yan, Ruile Shen |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23650 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |