Integrative analysis of semen quality and metabolomic profiles reveals breed-specific biomarker fertility in Indonesian buffalo

Sigit Bintara, Kurniawan Dwi Prihantoko, Aeni Nurlatifah, Tulus Maulana, Athhar Manabi Diansyah, Sitti Nurhaliza, Rahmat Rahmat, Muhammad Fajar Amrullah · 2025

Read Integrative analysis of semen quality and metabolomic profiles reveals breed-specific biomarker fertility in Indonesian buffalo by Sigit Bintara, Kurniawan Dwi Prihantoko, Aeni Nurlatifah, Tulus Maulana, Athhar Manabi Diansyah, Sitti Nurhaliza, Rahmat Rahmat, Muhammad Fajar Amrullah (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13314335.txt.

Description

Breeding buffalo in Indonesia depends on semen that survives freezing well, and breeds may differ in that trait. Sigit Bintara and co-authors studied three local breeds in 2025, Silangit, Toraja, and Sapala. They measured thawed sperm quality with computer tools and profiled the small molecules in the semen with high-resolution lab methods.

Silangit bulls showed higher sperm viability and membrane integrity, while the other breeds had fewer abnormal sperm shapes. Each breed also carried its own pair of marker molecules, tied to energy use, membrane repair, or defense against cell damage. Tests confirmed the markers could sort the breeds. The authors say such markers could guide fertility prediction and selective breeding.

Catalog record

CREATORSigit Bintara, Kurniawan Dwi Prihantoko, Aeni Nurlatifah, Tulus Maulana, Athhar Manabi Diansyah, Sitti Nurhaliza, Rahmat Rahmat, Muhammad Fajar Amrullah
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE30 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13314335

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