Lessons learned from different prognostic factors analysis in intermediate-risk neuroblastoma: ten years’ experience at a tertiary center
Mustafa Selim, Hanafy Hafez, Abeer M Elsayed, Mohamed Shalaby, Abdalwahab R Abdalwahab, Soad A Eltokhy, Mohamed Fawzy · 2025
Read Lessons learned from different prognostic factors analysis in intermediate-risk neuroblastoma: ten years’ experience at a tertiary center by Mustafa Selim, Hanafy Hafez, Abeer M Elsayed, Mohamed Shalaby, Abdalwahab R Abdalwahab, Soad A Eltokhy, Mohamed Fawzy (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13313431.txt.
Description
Mustafa Selim and co-authors review ten years of mid-risk childhood nerve tumors in a 2025 study. Neuroblastoma at intermediate risk covers a wide range of behavior. The Egyptian center treated fifty children between 2007 and 2016. The team asked who benefits from surgery and what predicts survival, especially when early chemotherapy works slowly.
Response to the first chemo cycles was weak at first, then rose by the end of treatment. Seventy percent had surgery, more often among slow responders. Early response predicted both whether surgery proved feasible and the final disease state. Five-year survival reached eighty-four percent. For slow responders, surgery clearly improved the end-of-treatment picture. The lessons help centers weigh operating on children whose tumors answer drugs slowly.
Catalog record
| CREATOR | Mustafa Selim, Hanafy Hafez, Abeer M Elsayed, Mohamed Shalaby, Abdalwahab R Abdalwahab, Soad A Eltokhy, Mohamed Fawzy |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |