MRI-based correlates of brain changes and quality of life outcomes following radiotherapy for head and neck cancer
Noor Shatirah Voon, Kah Hui Yap, Noorazrul Yahya · 2026
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Description
Radiation therapy for head and neck cancer can affect brain areas tied to thinking, mood, and social life. Noor Shatirah Voon, Kah Hui Yap, and Noorazrul Yahya studied 100 patients in 2026 who had scans and quality-of-life surveys before and after treatment. They measured dose to the brain and volume changes in four regions, including the hippocampus and thalamus.
Higher treatment dose linked to lower quality of life across general health and physical, emotional, cognitive, and social scores. Sex and cancer stage also played a part. Brain volume changes helped predict who fared worse. The authors suggest pairing routine brain imaging with dose planning to spot at-risk patients early.
Catalog record
| CREATOR | Noor Shatirah Voon, Kah Hui Yap, Noorazrul Yahya |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |