Monitoring the safety of the adjuvanted human papillomavirus vaccine HPV-16/18-AS04 in association with pregnancy and potential immune-related diseases in China: A retrospective observational cohort study

Junting Yang, Adoración Navarro-Torné, Zhike Liu, Jinxin Guo, Siwei Deng, Ruogu Meng, Yu Yang, Rhed Evans, Amila Poddar, Huifeng Yun, Siyan Zhan · 2026

Read Monitoring the safety of the adjuvanted human papillomavirus vaccine HPV-16/18-AS04 in association with pregnancy and potential immune-related diseases in China: A retrospective observational cohort study by Junting Yang, Adoración Navarro-Torné, Zhike Liu, Jinxin Guo, Siwei Deng, Ruogu Meng, Yu Yang, Rhed Evans, Amila Poddar, Huifeng Yun, Siyan Zhan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13313177.txt.

Description

Junting Yang and co-workers report a large safety study from China, published in 2026, on a vaccine that guards against human papillomavirus. Their work tracks the HPV-16/18 vaccine with the AS04 adjuvant, sold as Cervarix, and looks for links to pregnancy outcomes and diseases of the immune system.

The team used health records from the Yinzhou platform for the years 2010 to 2020, covering people aged 9 to 45 years. Of 1,002,399 people in the records, 891,463 met the study rules, and vaccine uptake was 11.95 per 1000 persons in the target age group. Rates of a few spine and lung diseases were higher in vaccinated women. Yet the authors could not show the vaccine caused them, since other factors and wrong codes may explain the gap.

Catalog record

CREATORJunting Yang, Adoración Navarro-Torné, Zhike Liu, Jinxin Guo, Siwei Deng, Ruogu Meng, Yu Yang, Rhed Evans, Amila Poddar, Huifeng Yun, Siyan Zhan
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE62710
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13313177

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