Depression and risk of incident heart diseases among older adults at CKM stages 0–3: evidence from the China Health and Retirement Longitudinal Study
Deling Zeng, Feifei Xu, Yanyuan Zhang, Lingxiao Zhou, Shurong Zhang, Yanqing Wang, Fengyi Duan · 2026
Read Depression and risk of incident heart diseases among older adults at CKM stages 0–3: evidence from the China Health and Retirement Longitudinal Study by Deling Zeng, Feifei Xu, Yanyuan Zhang, Lingxiao Zhou, Shurong Zhang, Yanqing Wang, Fengyi Duan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13312823.txt.
Description
Deling Zeng and colleagues examine, in a 2026 study, whether depression raises the risk of new heart disease in older adults already staged within the cardiovascular-kidney-metabolic syndrome framework. Evidence for this group was scarce, so the team turned to the China Health and Retirement Longitudinal Study for participants at syndrome stages 0 to 3.
Among 4,738 participants, those screening positive for depression carried significantly higher odds of later ischemic heart disease after adjustment, with an odds ratio of 1.62, and even higher odds of progressing to stage 4 disease. The pattern survived six sensitivity analyses, held across subgroups, and rose in a straight line with depression scores. Tests found no sign that body mass, inflammation markers, or white cell counts carried the effect. The authors argue depression deserves a place in heart risk assessment for ageing patients.
Catalog record
| CREATOR | Deling Zeng, Feifei Xu, Yanyuan Zhang, Lingxiao Zhou, Shurong Zhang, Yanqing Wang, Fengyi Duan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35813 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |