Prevention of cognitive decline and dementia: Current evidence on lifestyle factors and dietary patterns
Ligia J. Dominguez, Nicola Veronese, Francesco Saverio Ragusa, Flavia Seminara, Salvatore Maria Baio, Laura Vernuccio, Giuseppina Catanese, Mario Barbagallo · 2026
Read Prevention of cognitive decline and dementia: Current evidence on lifestyle factors and dietary patterns by Ligia J. Dominguez, Nicola Veronese, Francesco Saverio Ragusa, Flavia Seminara, Salvatore Maria Baio, Laura Vernuccio, Giuseppina Catanese, Mario Barbagallo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13312793.txt.
Description
Ligia J. Dominguez and co-authors review, in a 2026 narrative synthesis, what lifestyle and diet can do to prevent cognitive decline and dementia. More than 55 million people live with dementia today, a number expected to reach roughly 153 million by 2050, and no strong disease-modifying therapy exists. Against that backdrop, evidence suggests up to 45 percent of cases trace to modifiable factors spread across the life course.
The review weighs diet, physical activity, smoking, alcohol, sleep, and social and mental engagement, drawing on large cohorts, meta-analyses, umbrella reviews, and multidomain trials. Mediterranean, DASH, and MIND eating patterns associate with better cognitive outcomes, while unhealthy patterns raise risk. Yet the authors stress open questions about causality, the best ages to intervene, and which components matter most, alongside thin randomized evidence and narrow study populations. Their synthesis maps where prevention advice stands on firm ground and where it does not.
Catalog record
| CREATOR | Ligia J. Dominguez, Nicola Veronese, Francesco Saverio Ragusa, Flavia Seminara, Salvatore Maria Baio, Laura Vernuccio, Giuseppina Catanese, Mario Barbagallo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |