Comprehensive genomic insights into lineages, virulence, and antibiotic resistance profiles of Campylobacter jejuni entailing a global One Health scenario

Shamsul Qumar, Mohamad Hamad, Raed AbuOdeh, Ghalia Khoder, Niyaz Ahmed · 2026

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Description

Shamsul Qumar and co-authors present a 2026 global genomic analysis of Campylobacter jejuni, a leading cause of bacterial food poisoning for which poultry is a major reservoir. Heavy antibiotic use in livestock has bred multidrug-resistant strains, so the team compared genomes from human and chicken hosts in a One Health frame linking animal and human risk.

The analysis covered 1,125 high-quality genomes, including five newly sequenced chicken isolates, and sorted their genes into 4,489 clusters with a conserved core of 1,360. Family trees split into three big clades with little regard for geography; human strains appeared everywhere, while chicken strains concentrated in one clade, hinting at host adaptation. All five new isolates resisted several drugs. Across the set, 31 known resistance genes turned up, underlining the scale of the resistance problem.

Catalog record

CREATORShamsul Qumar, Mohamad Hamad, Raed AbuOdeh, Ghalia Khoder, Niyaz Ahmed
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE67903
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13312522

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