Emerging role of microRNAs as modulators of the tumor immune microenvironment
Rachele Frigerio, Arianna Ortolano, Gennaro Ciliberto, Rita Mancini, Luigi Fattore · 2026
Read Emerging role of microRNAs as modulators of the tumor immune microenvironment by Rachele Frigerio, Arianna Ortolano, Gennaro Ciliberto, Rita Mancini, Luigi Fattore (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13311767.txt.
Description
Rachele Frigerio and co-authors review how small RNAs called microRNAs reshape the immune setting around tumors in a 2026 article. This immune setting decides whether checkpoint drugs work or fail.
The review traces how tumor microRNAs blunt antigen display, tune checkpoint pathways, sap killer cell attack, grow suppressor cell groups, and rewire support tissue and metabolism. It then weighs treatments that block harmful microRNAs or restore helpful ones, ideally paired with checkpoint drugs. Few such pairs have reached clinic testing. Better lab models that copy the human tumor setting are needed to move pairs forward.
Catalog record
| CREATOR | Rachele Frigerio, Arianna Ortolano, Gennaro Ciliberto, Rita Mancini, Luigi Fattore |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 59515 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |