Influence of sex and systemic lupus erythematosus disease status on cerebral cortex structure

Yifan Yang, Li Tao, Ruotong Zhao, Ru Bai, Shuang Liu, Guofang Zhang, Shu Li, Xinyu Xu, Yuqi Cheng, Jian Xu · 2026

Read Influence of sex and systemic lupus erythematosus disease status on cerebral cortex structure by Yifan Yang, Li Tao, Ruotong Zhao, Ru Bai, Shuang Liu, Guofang Zhang, Shu Li, Xinyu Xu, Yuqi Cheng, Jian Xu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13311624.txt.

Description

Yifan Yang and colleagues, in 2026, present a brain scan study on how sex and lupus status together shape the cortex. Lupus can affect the brain, and its course differs sharply by sex.

The study scanned 196 people: 30 men and 66 women with lupus, plus 33 male and 67 female healthy controls. Measures covered cortical thickness, folding, and groove depth in set regions. Two spots showed a clear sex-by-disease interplay, one in a left orbital groove and one in a left frontal groove. Thickness ran lower in lupus across much of both hemispheres. No firm link to disease activity scores appeared.

Catalog record

CREATORYifan Yang, Li Tao, Ruotong Zhao, Ru Bai, Shuang Liu, Guofang Zhang, Shu Li, Xinyu Xu, Yuqi Cheng, Jian Xu
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE50408
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13311624

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