Understanding the Molecular Landscape of Alopecia Areata: Key Genes, Regulatory Networks, and Therapeutic Targets
Ahmed Ibrahim AbdElneam, Mohammed Saleh Al‐Dhubaibi, Saleh Salem Bahaj, Ghada Farouk Mohammed, Lina Mohammed Atef · 2026
Read Understanding the Molecular Landscape of Alopecia Areata: Key Genes, Regulatory Networks, and Therapeutic Targets by Ahmed Ibrahim AbdElneam, Mohammed Saleh Al‐Dhubaibi, Saleh Salem Bahaj, Ghada Farouk Mohammed, Lina Mohammed Atef (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13311371.txt.
Description
Ahmed Ibrahim AbdElneam and co-authors map the gene landscape of alopecia areata in a 2026 data study. In this autoimmune illness, the immune system attacks hair roots and causes patchy hair loss.
Gene data from a public set comparing patients and healthy controls yielded 5134 genes with changed activity. Network tools picked out ten hub genes, among them CCL5, CCR7, and CXCL9, plus leading control factors such as FOXP3. Chemokine signaling and cytokine pathways stood out. The study also predicts 49 small RNAs that may steer these genes. The map points to targets that future drugs for hair regrowth could aim at.
Catalog record
| CREATOR | Ahmed Ibrahim AbdElneam, Mohammed Saleh Al‐Dhubaibi, Saleh Salem Bahaj, Ghada Farouk Mohammed, Lina Mohammed Atef |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22407 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |