Investigating the prognostics and theranostic cell cycle-related genes of Hinokinin in high-grade glioma: an integrated network pharmacology, bioinformatics, and molecular docking approach
Oukhdouch Anass, Nadir Youssef, Salman El mostafa, Jebhi Khalid, Zinbi Basma, Sellami Souad, Rais Hanane · 2026
Read Investigating the prognostics and theranostic cell cycle-related genes of Hinokinin in high-grade glioma: an integrated network pharmacology, bioinformatics, and molecular docking approach by Oukhdouch Anass, Nadir Youssef, Salman El mostafa, Jebhi Khalid, Zinbi Basma, Sellami Souad, Rais Hanane (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13311168.txt.
Description
Oukhdouch Anass and colleagues map a plant compound against high grade glioma through network methods in a 2026 study. Glioblastoma is the most harsh adult brain tumor, and runaway cell cycling drives its growth. Hinokinin from a pepper plant shows anti cancer signs, yet its glioma targets were unknown.
Gene databases, target forecasts, and docking tools were joined in one pipeline. Thirty six shared genes emerged, rich in cycle control and kinase roles. Five hub genes stood out, all raised in tumors and tied to poor survival and p53 path faults. Docking and drug trait checks backed hinokinin fit. Lab tests must confirm the map.
Catalog record
| CREATOR | Oukhdouch Anass, Nadir Youssef, Salman El mostafa, Jebhi Khalid, Zinbi Basma, Sellami Souad, Rais Hanane |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49957 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |