CDC20 promotes prostate cancer progression via modulating c-MYC and PI3K-AKT signaling
Jixiang Ding, Xinyu Xu, Ningning Zhang, Jiaojiao Chen, Wenhui Zhu, Ke Lu, Chaozhong Wang, Zhenyu Fu, Jing Zhai, Yizhou Wang · 2026
Read CDC20 promotes prostate cancer progression via modulating c-MYC and PI3K-AKT signaling by Jixiang Ding, Xinyu Xu, Ningning Zhang, Jiaojiao Chen, Wenhui Zhu, Ke Lu, Chaozhong Wang, Zhenyu Fu, Jing Zhai, Yizhou Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13311138.txt.
Description
Jixiang Ding and co-authors study a cell division driver in prostate cancer growth in a 2026 paper. Prostate cancer outcomes vary widely, so firm markers and drivers are needed. A gene called CDC20 stood out in a large atlas as a solo outlook factor with high levels in tumors.
In two cell lines, raising CDC20 sped growth, movement, invasion, and cycle advance, while cutting it slowed all four. The protein binds the growth driver c-MYC and shapes a key growth signal path. In mouse grafts, cutting CDC20 shrank tumors and boosting it sped growth. The gene may serve both outlook grading and drug targeting.
Catalog record
| CREATOR | Jixiang Ding, Xinyu Xu, Ningning Zhang, Jiaojiao Chen, Wenhui Zhu, Ke Lu, Chaozhong Wang, Zhenyu Fu, Jing Zhai, Yizhou Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54356 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |