Lysosome-dependent cell death in hepatocellular carcinoma: unlocking the therapeutic potential of natural products
Yijing Xu, Ruixin Wang, Xiaofang Xie, Huali Fan, Fu Peng · 2026
Read Lysosome-dependent cell death in hepatocellular carcinoma: unlocking the therapeutic potential of natural products by Yijing Xu, Ruixin Wang, Xiaofang Xie, Huali Fan, Fu Peng (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13311099.txt.
Description
Yijing Xu and co-authors review lysosome driven cell death as a liver cancer target in a 2026 paper. Liver cancer resists many targeted drugs, so a death path that bypasses the usual route draws interest. When lysosome walls leak, cutting enzymes spill and kill the cell from inside.
Natural compounds can trigger that leak through several routes, such as blocking a fat enzyme, freeing iron, shifting acidity, or cutting a growth switch. Such compounds also free trapped drugs from swollen lysosomes, which pairs well with standard targeted drugs. Work joins past proof from major databases to guide resistant cancer care.
Catalog record
| CREATOR | Yijing Xu, Ruixin Wang, Xiaofang Xie, Huali Fan, Fu Peng |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 80676 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |