Engineering biomimetic tarsal microtissue via structurally zoned hydrogel scaffold for integrated eyelid reconstruction
Xindi Liu, Ke Yao, Meizhu Wang, Xuri Chen, Zhichu Chen, Zheren Sun, Xuanhe Lin, Nianjia Wang, Chunlei Yao, Shenyu Huang, Yijie Wang, Qi Gao, Yong He, Juan Ye · 2026
Read Engineering biomimetic tarsal microtissue via structurally zoned hydrogel scaffold for integrated eyelid reconstruction by Xindi Liu, Ke Yao, Meizhu Wang, Xuri Chen, Zhichu Chen, Zheren Sun, Xuanhe Lin, Nianjia Wang, Chunlei Yao, Shenyu Huang, Yijie Wang, Qi Gao, Yong He, Juan Ye (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13310939.txt.
Description
Xindi Liu led a 2026 study that builds a living eyelid support tissue from a zoned gel scaffold. The tarsus plate gives the eyelid its shape and holds oil glands that guard the eye surface. Loss of the plate harms both support and oil flow, and current substitutes fail to copy both roles.
A light printed gel copied the layered build of natural tarsus, then salt and stretch steps raised its strength and flex. Human oil gland cells, matured with a drug cue, were seeded to form the tissue. Grafts placed in rat eyelid gaps gave support and aided regrowth. The joint plan may improve eye surface health.
Catalog record
| CREATOR | Xindi Liu, Ke Yao, Meizhu Wang, Xuri Chen, Zhichu Chen, Zheren Sun, Xuanhe Lin, Nianjia Wang, Chunlei Yao, Shenyu Huang, Yijie Wang, Qi Gao, Yong He, Juan Ye |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 106274 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |