Case Report: Immune checkpoint inhibitor-associated myocarditis, myositis, and myasthenia gravis overlap syndrome with flow cytometric phenotyping before and after treatment in a patient with urothelial carcinoma

Karen Gambina, Carly Tymm, Matthieu Paiola, Kurenai Tanji, John Zech, Robert Winchester, Adam Mor, Yevgeniya Gartshteyn · 2026

Read Case Report: Immune checkpoint inhibitor-associated myocarditis, myositis, and myasthenia gravis overlap syndrome with flow cytometric phenotyping before and after treatment in a patient with urothelial carcinoma by Karen Gambina, Carly Tymm, Matthieu Paiola, Kurenai Tanji, John Zech, Robert Winchester, Adam Mor, Yevgeniya Gartshteyn (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13310926.txt.

Description

Karen Gambina reports a 2026 case of a triple immune side effect after cancer immunotherapy. A woman aged 77 years got a PD-1 blocking drug for bladder cancer and then grew weak with drooping lids and slurred speech. Tests pointed to joint harm of heart muscle, skeletal muscle, and nerve muscle signaling at once.

Strong steroids, a second immune calming drug, and antibody infusions cleared her symptoms. Blood cell profiling before, during, and after care showed memory killer cells surged at flare. A worn effector cell subset tracked disease activity and shrank with steroids. Cell tracking may guide care for rare immune harms.

Catalog record

CREATORKaren Gambina, Carly Tymm, Matthieu Paiola, Kurenai Tanji, John Zech, Robert Winchester, Adam Mor, Yevgeniya Gartshteyn
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE26538
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13310926

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