Evaluating completeness, coherence, and consistency of genome-scale function annotations
Rund Tawfiq, Maxat Kulmanov, Robert Hoehndorf · 2026
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Description
Rund Tawfiq and co-authors set three whole-web tests for gene fare marks: full, in-step, and clash-free. Stock marks tag one protein at a time, as if each worked lone. True proteins work in webs, where fare hangs on kin and place. Their 2026 tests ask: are core fares all there, do fare chains hold, and do barred pairs stay parted? Hand-kept marks of six model kinds and calls from seven tools are put to the tests.
Hand marks pass most bars. Tool calls fail them as a flock, though their per-protein marks can read fine. The gap is a yard stick: fare calls must be judged as webs, not as tags.
Catalog record
| CREATOR | Rund Tawfiq, Maxat Kulmanov, Robert Hoehndorf |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 72 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |