HOX gene dysregulation in head and neck squamous cell carcinoma: mechanisms, clinical relevance, and future perspectives
Norma Carolina Hernandez-Bautista, Claudia Altamirano-Torres, Jose Manuel Vazquez-Guillen, Reyes S. Tamez-Guerra, Cristina Rodríguez-Padilla, Diana Resendez-Perez · 2026
Read HOX gene dysregulation in head and neck squamous cell carcinoma: mechanisms, clinical relevance, and future perspectives by Norma Carolina Hernandez-Bautista, Claudia Altamirano-Torres, Jose Manuel Vazquez-Guillen, Reyes S. Tamez-Guerra, Cristina Rodríguez-Padilla, Diana Resendez-Perez (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13310739.txt.
Description
Norma Carolina Hernandez-Bautista and co-authors review HOX genes in head and neck cancer in a 2026 mini review. HOX genes guide body pattern in early life and control cell growth, movement, and survival in adult tissue. When their activity goes wrong, cancers of the mouth and throat may grow, spread, and resist drugs.
Humans carry 39 HOX genes in four clusters across four chromosomes. The review sums up how each gene can act as a growth driver or a brake, based on context. It also weighs use as warning signs and drug targets. Gaps remain, and the authors call for tests that prove which changes truly drive disease.
Catalog record
| CREATOR | Norma Carolina Hernandez-Bautista, Claudia Altamirano-Torres, Jose Manuel Vazquez-Guillen, Reyes S. Tamez-Guerra, Cristina Rodríguez-Padilla, Diana Resendez-Perez |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26199 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |