Loss of hepatocyte PI3Kα reduces hepatocellular carcinoma and hepatocyte proliferation in association with altered lipid metabolism
Barbara Becattini, Claudia Sardi, Bart Edelbroek, Amit Chand Gupta, Toshima Parris, Khalil Helou, Giovanni Solinas · 2026
Read Loss of hepatocyte PI3Kα reduces hepatocellular carcinoma and hepatocyte proliferation in association with altered lipid metabolism by Barbara Becattini, Claudia Sardi, Bart Edelbroek, Amit Chand Gupta, Toshima Parris, Khalil Helou, Giovanni Solinas (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13310634.txt.
Description
Background & AimsHepatocellular carcinoma (HCC) is a disease with an increasing incidence and a high mortality rate. Thus, targeted therapies for HCC are urgently needed. Phosphoinositide 3-kinase (PI3K)-AKT-mTORC1 signaling is frequently induced in solid tumors and is associated with tumor progression and with the most aggressive type of HCC.
Catalog record
| CREATOR | Barbara Becattini, Claudia Sardi, Bart Edelbroek, Amit Chand Gupta, Toshima Parris, Khalil Helou, Giovanni Solinas |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |