Identification of Bone Marrow and Peripheral Blood Plasma Extracellular Vesicle Protein Biomarker Signatures for Multiple Myeloma Diagnosis and Staging

Angelique Cheryl, Rebecca Sheridan, Kieran Brennan, Despina Bazou, David Matallanas, Peter O’Gorman, Luis F Iglesias-Martinez, Margaret M Mc Gee · 2026

Read Identification of Bone Marrow and Peripheral Blood Plasma Extracellular Vesicle Protein Biomarker Signatures for Multiple Myeloma Diagnosis and Staging by Angelique Cheryl, Rebecca Sheridan, Kieran Brennan, Despina Bazou, David Matallanas, Peter O’Gorman, Luis F Iglesias-Martinez, Margaret M Mc Gee (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13310408.txt.

Description

Angelique Cheryl and co-authors hunt for blood and marrow parcel markers of multiple myeloma in a 2026 study. Myeloma is a cancer of plasma cells in bone marrow that still lacks a cure. Diagnosis needs a marrow biopsy, an invasive test patients repeat over the disease course.

Parcels shed by cells, called extracellular vesicles, were gathered from blood and marrow fluid of 33 patients and 12 healthy donors. Protein cargo was profiled by mass measurement, and learning models built signatures for early stage, active disease, and relapse states. Scoring tests judged how cleanly the signatures separated the states. The authors present parcel proteins as a possible needle-free liquid biopsy for staging and tracking.

Catalog record

CREATORAngelique Cheryl, Rebecca Sheridan, Kieran Brennan, Despina Bazou, David Matallanas, Peter O’Gorman, Luis F Iglesias-Martinez, Margaret M Mc Gee
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE72311
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13310408

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