Cardiopulmonary Exercise Testing and Quantitative Chest CT in COPD: The Stronger Association of Emphysema Over Airway Thickness with Functional Impairment
Yaodie Peng, Minghui Shi, Chunyan Yu, Ting Yang, Ke Huang · 2026
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Description
Yaodie Peng and co-authors relate lung exercise capacity to airway and air-sac damage in COPD in a 2026 study. Chronic obstructive pulmonary disease narrows airways and destroys air sacs in differing mixes per patient. Whether air-sac loss or airway thickening tracks exercise limits more closely was unclear.
Ninety-three stable patients underwent lung function tests, chest CT scans, and exercise testing. Scan measures split patients into four types: normal, air-sac dominant, airway dominant, and mixed. Air-sac dominant and mixed patients showed worse airflow ratios in the reported results. Statistical models tied each scan measure to exercise outcomes. The authors conclude air-sac damage tracks exercise capacity more strongly than airway thickness in this group.
Catalog record
| CREATOR | Yaodie Peng, Minghui Shi, Chunyan Yu, Ting Yang, Ke Huang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25857 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |