The involvement of circular RNAs in breast cancer metastasis: Insight into EMT-related signaling pathways
Mehran Molavand, Maryam Majidinia, Bahman Yousefi · 2026
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Description
Mehran Molavand, Maryam Majidinia, and Bahman Yousefi review how circular RNAs help breast cancer spread, in a review paper from 2026. Circular RNAs are ring-shaped RNA molecules that regulate gene activity. Spread to distant organs is the main driver of breast cancer deaths.
A key step in spread is a change called epithelial-to-mesenchymal transition, in which cells loosen and become mobile. Circular RNAs feed into several signaling pathways that drive this change, and they switch on its master transcription factors. They also affect how cells grip their surroundings and cut through tissue. The authors note these RNAs could serve as markers for early detection and outlook, and as drug targets.
Catalog record
| CREATOR | Mehran Molavand, Maryam Majidinia, Bahman Yousefi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 65 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |