A primary care pharmacogenetic precision medicine pilot based on specific Māori tribal ethical frameworks and principles
Stephen P Robertson, Benjamin J Halliday, Rhonda Tibble, Caroline Koia, Tuta Haereroa, Elizabeth Goodin, Ben Curran, Claire E Rye, Helen Wihongi, Ben Te Aika, Joep de Ligt, Donia Macartney-Coxson, Nick Jones, Jun Huh, E Owen Perkins, Matt Pestle, Kenny Zhao, Martin A Kennedy, Patrick A Gladding, David M Markie, Cristin G Print, Phillip L Wilcox, Huti Puketapu-Watson · 2026
Read A primary care pharmacogenetic precision medicine pilot based on specific Māori tribal ethical frameworks and principles by Stephen P Robertson, Benjamin J Halliday, Rhonda Tibble, Caroline Koia, Tuta Haereroa, Elizabeth Goodin, Ben Curran, Claire E Rye, Helen Wihongi, Ben Te Aika, Joep de Ligt, Donia Macartney-Coxson, Nick Jones, Jun Huh, E Owen Perkins, Matt Pestle, Kenny Zhao, Martin A Kennedy, Patrick A Gladding, David M Markie, Cristin G Print, Phillip L Wilcox, Huti Puketapu-Watson (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13310208.txt.
Description
Stephen P Robertson and co-authors describe a gene-guided prescribing pilot built with a Māori tribal community in a 2026 article. Indigenous communities are often left out of genomic medicine research and may hold distinct cultural views on genetic data. The pilot ran on a platform shaped by Māori ethical frameworks.
Community talks held face to face guided the design, with study stories rooted in tribal history to support joining. Genome data for 148 Māori participants were checked for variants in CYP2C19, a gene that changes how many drugs are processed, and matched against a year of prescriptions. About 7 percent were predicted poor metabolizers and 11 percent rapid ones in the pilot counts. The authors offer the process as proof of principle for tribal-led precision care.
Catalog record
| CREATOR | Stephen P Robertson, Benjamin J Halliday, Rhonda Tibble, Caroline Koia, Tuta Haereroa, Elizabeth Goodin, Ben Curran, Claire E Rye, Helen Wihongi, Ben Te Aika, Joep de Ligt, Donia Macartney-Coxson, Nick Jones, Jun Huh, E Owen Perkins, Matt Pestle, Kenny Zhao, Martin A Kennedy, Patrick A Gladding, David M Markie, Cristin G Print, Phillip L Wilcox, Huti Puketapu-Watson |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36216 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |