Lactoferrin Displays Stimulating and Protective Effects on Newly Isolated Phage vB_Sau-E: A New Perspective for Treatment of Staphylococcal Skin Infections
Urszula Leszczyńska, Małgorzata Stasiłojć, Milena Grzenkowicz, Magdalena Narajczyk, Agnieszka Necel, Lidia Piechowicz, Katarzyna Kosznik-Kwaśnicka, Anna Żywicka · 2026
Read Lactoferrin Displays Stimulating and Protective Effects on Newly Isolated Phage vB_Sau-E: A New Perspective for Treatment of Staphylococcal Skin Infections by Urszula Leszczyńska, Małgorzata Stasiłojć, Milena Grzenkowicz, Magdalena Narajczyk, Agnieszka Necel, Lidia Piechowicz, Katarzyna Kosznik-Kwaśnicka, Anna Żywicka (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13306224.txt.
Description
Urszula Leszczyńska and co-authors study in 2026 whether the immune protein lactoferrin can help a newly isolated virus that attacks Staphylococcus aureus. Phages, viruses that infect bacteria, offer an alternative when antibiotics fail against resistant skin infections. The phage, named vB_Sau-E, was characterised for growth and killing range.
The phage infected twelve of twenty-two resistant clinical isolates, with a life cycle near thirty minutes. Lactoferrin raised plating efficiency and kept the phage stable at mild acidity and in frozen storage. Combined use also added antibacterial effect, although strength varied by strain. Skin cell tests supported compatibility with human tissue models. The authors propose lactoferrin as a stabilising partner for phage treatment of staphylococcal skin infections, especially where biofilms block antibiotics.
Catalog record
| CREATOR | Urszula Leszczyńska, Małgorzata Stasiłojć, Milena Grzenkowicz, Magdalena Narajczyk, Agnieszka Necel, Lidia Piechowicz, Katarzyna Kosznik-Kwaśnicka, Anna Żywicka |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |