Neuroprotective effects of ursodeoxycholic acid in Parkinson's disease and Alzheimer's disease
Ashley En Yi Chong, Andrew Octavian Sasmita, Rhun Yian Koh, Anna Pick Kiong Ling · 2026
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Description
Ashley Chong and co-authors review a bile acid as a possible brain shield in a 2026 paper. The compound, UDCA, is a water friendly bile acid long used for liver care. The diseases in view are Parkinson's and Alzheimer's, which share cell power failure, oxidative stress, and toxic protein build up. Current drugs ease symptoms but do not slow the course.
Studies in cells and animals show the compound restores cell power, curbs cell death and swelling in the brain, and helps clear toxic clumps. Motor and thinking results improved in animal tests. Human proof is early: a Parkinson's trial looked safe and promising, while Alzheimer's data stay thin.
Catalog record
| CREATOR | Ashley En Yi Chong, Andrew Octavian Sasmita, Rhun Yian Koh, Anna Pick Kiong Ling |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 75 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |