Nasal Cytology as a Local Biomarker of Airway Inflammation: A Paradigm Shift in Precision Medicine
Matteo Gelardi · 2026
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Description
Matteo Gelardi sets out a 2026 proposal that nasal cytology should serve as a local marker of airway inflammation. Blood tests dominate current practice, yet they only hint at what happens inside the nasal lining. Examining cells taken from the nose is simple, non-invasive, and repeatable.
Gelardi argues that eosinophils reflect longer-lasting inflammation while mast cells mark more active phases of disease. When both cell types appear together, disease may be more severe. Adding cytology results to a combined clinical grading system could sharpen patient grouping, especially in chronic rhinosinusitis with nasal polyps. The proposal is framed as testable in ordinary clinics and research settings, rather than as settled practice.
Catalog record
| CREATOR | Matteo Gelardi |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |