Complexes of Zinc(II) Chloride with N-Vinyl-, N-Allyl- and N-Propargylimidazoles: Structural, Theoretical and Biological Studies
Vladimir S. Tyurin, Victoria S. Babasieva, Mikhail S. Grigoriev, Lidiya N. Parshina, Ilya A. Zamilatskov, Elena A. Smolyarchuk, Olga V. Nesterova, Vladislav N. Turenko, Tatiana I. Kolyganova, Vera G. Arzumanian, Kerim Mutig, Mikhail Yu. Samsonov, Svetlana A. Lebedeva · 2026
Read Complexes of Zinc(II) Chloride with N-Vinyl-, N-Allyl- and N-Propargylimidazoles: Structural, Theoretical and Biological Studies by Vladimir S. Tyurin, Victoria S. Babasieva, Mikhail S. Grigoriev, Lidiya N. Parshina, Ilya A. Zamilatskov, Elena A. Smolyarchuk, Olga V. Nesterova, Vladislav N. Turenko, Tatiana I. Kolyganova, Vera G. Arzumanian, Kerim Mutig, Mikhail Yu. Samsonov, Svetlana A. Lebedeva (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13305716.txt.
Description
Vladimir S. Tyurin, Victoria S. Babasieva, and co-authors study, in a 2026 paper, zinc complexes built from imidazole ligands carrying vinyl, allyl, and propargyl arms, as candidate metal-based drugs. Metal complexes can outperform their free ligands, and zinc offers low toxicity plus flexible geometry. The team made new members of the family, solved their crystal structures, and modeled their electronic properties by computer.
Testing cast a wide net: wound healing and oxygen-deprivation protection in animals, microbes, and five cell lines. Anti-microbe effects were modest, though antifungal action stood out against Candida. Cell killing concentrated in cervical cancer and rhabdomyosarcoma cell lines. Computer predictions of activity spectra agreed with the measured spread. The authors nominate the complexes as lead structures whose balance of actions earns further tuning toward usable drugs.
Catalog record
| CREATOR | Vladimir S. Tyurin, Victoria S. Babasieva, Mikhail S. Grigoriev, Lidiya N. Parshina, Ilya A. Zamilatskov, Elena A. Smolyarchuk, Olga V. Nesterova, Vladislav N. Turenko, Tatiana I. Kolyganova, Vera G. Arzumanian, Kerim Mutig, Mikhail Yu. Samsonov, Svetlana A. Lebedeva |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |