Bidirectional Feedback Between Metabolic Reprogramming and Epithelial–Mesenchymal Transition: From Mechanisms to Therapeutic Interventions
Yuxin Liu, Mengke Wang, Dan Liu, Hanning Lyu, Deru Zhang, Yang Sun · 2026
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Description
Yuxin Liu and co-authors wrote a 2026 review of the two way talk between cell shape change and fuel rewiring in cancer. Spread of tumors drives most cancer deaths, and a shape shift that frees cells to move sits near the heart of spread. Cells that shift shape also rebuild how they burn fuel.
Sugar, fat, and protein fuel paths join to feed the shift, build new membranes, and keep the cell's redox balance. In return, the waste and signal goods of those paths can steer the shift itself, through signals or gene marks. The review maps that loop in full and sums its role in tumor growth. It ends with care plans that strike the joint where the two processes meet.
Catalog record
| CREATOR | Yuxin Liu, Mengke Wang, Dan Liu, Hanning Lyu, Deru Zhang, Yang Sun |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |